Postdoctoral fellow
- Location
- Saint Louis, Missouri
- Salary
- $57,000- 65,000 depending on prior experience
- Posted
- 22 Mar 2023
- Closes
- 21 May 2023
- Ref
- Postdoc in chromatin and developmental biology
- Discipline
- Life Science
- Job Type
- Postdoctoral
- Employment - Hours
- Full time
- Duration
- Fixed term
- Qualification
- PhD
- Sector
- Academia
The project centers on an inner nuclear envelope protein, Nemp1, that we have found is critical for fertility in flies, worms, fish and mice (Tsatskis et al., 2020,Science Advances) . We discovered that NEMP supports nuclear envelope stiffness through interactions with LEM domain proteins. Our published and preliminary data in mice indicates that loss of Nemp1 leads to defects in chromatin organization in oocytes. The project will explore how Nemp1 in mice or Nemp in flies controls chromatin organization, nuclear envelope mechanics and genome activation.
A strong background in molecular biology, developmental biology, or cell biology is is required as is a PhD. Experience in mouse or fly development is a plus, as is experience in chromatin techniques such as ATAC-Seq, Hi-C and DAM-ID
Interested applicants should email a single PDF file consisting of a cover letter, curriculum vitae, a personal statement (including research interests and career goals) and should arrange for submission of three letters of reference to: mcneillh@wustl.edu More information on the McNeill lab can be found athttp://mcneilllab.wustl.edu/