PhD-student position focused on biophysical aspects of skin

Recruiter
Malmö University
Location
Malmö (Kommun), Skåne (SE)
Salary
Competitive
Posted
24 Mar 2023
Closes
14 Apr 2023
工作类型
PhD Studentship
Employment - Hours
Full time
Duration
Fixed term
Qualification
Masters
部门
Academia

About Malmö University

Malmö University is an innovative, urban and international institute of higher education, located in the centre of Malmö. We have around 1,800 employees and 24,000 students. Our research and education are characterised by the role we believe a university should play in an open society — to contribute to sustainability and equality in a scientifically grounded way with external partners and stakeholders. Identifying and addressing the challenges of the future are of highest priority. Our researchers and students work collaboratively to create, share and spread knowledge in order to understand, explain and develop society — both locally and globally.

The Department of Biomedical Science at Faculty of Health and Society (www.mau.se/bmv) offers programmes leading to a professional qualification as Prescriptionist and Biomedical laboratory scientist (both first cycle, 180 credits), and a Masters' programme, Biomedical Surface Science (second cycle, 120 credits), as well as first and second cycle freestanding courses. The Department negotiates the multifaceted intersection between biology, chemistry, medicine, physics, and technology and the interdisciplinary approach to research and education aims to further develop the theoretical and practical understanding of the complex subject matter. Drawing on the balance between basic and applied research, the Department has been successful in attracting funding from regional, national, and international research funding bodies. In addition, in the pursuit of possible applications, several industry funded contract research projects are currently running at the Department.

The research at the Department is also linked to our research center “Biofilms - Research Center for Biointerfaces” (www.mau.se/brcb), which combines biomedical science with clinical and translational research in medical, dental, food and environmental application areas in close collaboration with regional industry.

About the position

The main goal of the project is to explore the potential of further improving Photodynamic therapy (PDT) of skin cancers.

PDT is a treatment that involves light-sensitive medicine and a light source to destroy abnormal cells. It is currently used to treat a range of different indications such as, Basal Cell Carcinoma (BCC), Actinic Keratosis (AK), Bowens Disease, as well as other potential applications such as Acne and Psoriasis. Both BCC and AK have an increasing incidence rate in Sweden, and non-surgical treatment options are not well developed. With this project we therefore aim at exploring the potential of improving PDT of skin cancers. Successful PDT relies on three cornerstones, Light, Photosensitive Drug and Oxygen. It has been suggested that local administration of peroxides increases the levels of available oxygen in the skin. We would like to investigate whether topical administration of hydrogen peroxide containing cream increases the available levels of oxygen in the skin (and thus the strength of the photodynamic reaction) and for how long. Further, will the potential increase of oxygen and the degree of the reaction increase the effectiveness of PDT? In addition, we would continue to investigate what is the rate limiting factors of effective PDT? Current treatment of BCC is usually surgical removal of cancerous tissue, which lead to scarring. PDT is much less invasive and leaves less scaring after treatment, thus making it an interesting alternative for BCC treatment especially of the face and other sensitive areas, providing that efficacy can be proven.

The project combines an interdisciplinary team, involving Biofilms - Research Center for Biointerfaces at Malmö University and Bioglan AB as main partners. The expertise of current research team includes clinical sciences, cell/molecular biology, physical chemistry, pharmacy, and analytical chemistry. The preferred candidate has a background in pharmacy/chemistry/chemical engineering with emphasis on physical chemistry, surface and colloid chemistry, nanotechnology or analytical chemistry, and a strong interest in biomedical science.

PhD-student position in Biomedical Science

博士生将承认博士教育n at Malmö University. The PhD education will run for four years on 100% working time. The research topic is "Biomedical Science" and the faculty offers a Degree of Doctor of Philosophy in Medical Science. Provisions on appointment as a PhD student are laid out in the Swedish Higher Education Ordinance, Chapter 5. When making the appointment consideration must be given to the student's ability to benefit from studies.

In order to be considered for admission as a doctoral student, the applicant must meet the general and specific entry requirements for third-cycle courses and study programs and be considered in other respects to have the ability required to benefit from the course or study program. The higher education institution may permit an exemption from the general entry requirements for an individual applicant if there are special grounds. Ordinance (2010: 1064).

General entry requirements:

  1. a second-cycle higher education degree
  2. completed course requirements of at least 240 higher education credits, of which at least 60 higher education credits are second- cycle, or having in some other way, nationally or internationally, acquired equivalent knowledge.

Specific entry requirements:

  1. comprise at least 90 ECTS, of which 30 ECTS should be at second cycle level, in a subject which is of relevance for the research domain in question or which in some other way involve broadly equivalent knowledge.

Basis of assessment

The preferred candidate has a background in pharmacy/chemistry/chemical engineering with emphasis on physical chemistry, surface and colloid chemistry, nanotechnology or analytical chemistry, and a strong interest in biomedical science. Good communication skills in English (written and spoken) are necessary. Hands-on experience in the following techniques and topics is a strong merit: research related to the skin organ, neutron/x-ray scattering, FTIR spectroscopy, NMR, confocal Raman spectroscopy, confocal microscopy, Franz or flow-through diffusion cells, electrochemistry/electrical impedance spectroscopy.

In addition to formal competence, University employees must possess the personal capacities necessary to perform the duties of the position well and to represent the University in the best possible way. The successful candidate should have the ability to work in a team and collaborate with people in complementary disciplines.

Further information

约翰教授Engblom, +46 (0)70 6087525,johan.engblom@mau.se

Prof. Tautgirdas Ruzgas, +46 (0)40 6657431,tautgirdas.ruzgas@mau.se

For general questions regarding employment at Malmö university, contact HR-specialist Ewa-Marie Dahlgren, ewa-marie.dahlgren@mau.se

Malmö University kindly but firmly declines direct contact with recruiting and staffing agencies, as well as job advertising sellers.

Instructions to applicants

You apply through Malmo Universities' recruitment system by clicking the button "apply/ansök". As applicant, it is your own responsibility that the application is complete with all the documentation requested in the advertised position. Your application must be submitted to Malmö University no later than April 14st, 2023.

The application should contain the following

  1. A brief summary of scientific, teaching, and other qualifications relevant to the position
  2. Motivation letter for applying to this particular PhD-student position
  3. Signed list of qualifications (CV)
  4. Attested copies of certificates
  5. List of potential scientific publications
  6. Copy of a master/magister degree thesis or equivalent
  7. References (at least two; names, titles, contact information positions/relation)

Start date

As soon as possible

Union representatives

SACO-S: Ann-Mari Campbell,ann-marie.campbell@mau.se

Lärarförbundet: Peter Persson,peter-persson@mau.se

ST/OFR: Aje Carlbomaje.carlbom@mau.se

We are looking forward to receiving your application!

You apply no later than 14/04/2023 by clicking the apply button.

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